Dr. Ray Peat, Ph.D

Renowned Nutritional Counselor

Ray Peat acquired his PhD from the University of Oregon with a specialization in physiology. He started his work on hormones in 1968 and wrote his dissertation in 1972 in which he outlined his ideas on progesterone and the hormones closely related to it. His main thesis is that energy and structure are interdependent at every level.

The double bonds in Omega 3’s are anti-thyroid and pro-estrogen.

High cortisol and high estrogen cause leaky capillaries.

Methionine restriction increases lifespan 40%. 

Get enough milk when eating oatmeal.  Milk has calcium and anti-stress factors.

Cold foods causes a stress reaction and vascular restriction.  Could have a potentially deadly result.

Isotonic glucose solution for recovery from low energy production.

What are the benefits and methods of increasing your carbon dioxide?  Helps heart vessels relax and blood flow easily.  Bones get more dense.

Low carbon dioxide increases lactic acid.  A sign of overbreathing.

If at rest, the liver takes lactic acid out of the blood and makes glucose.  Need good thyroid function for that to happen.

Progesterone and thyroid support each other. 

Active thyroid hormone T-3 has 12 hour residency, thyroxine has 2 week residency in the body.

What should a listener with lymphocytic leukemia with high lymphocyte numbers do?.  Measure both lactic acid and carbon dioxide.  CO2 slows cell growth.  Take aspirin, which is anti-inflammatory.

Is baby aspirin good for the heart?  Is Reyes Syndrome a concern?  Is Tylenol responsible for toxic effects attributed to aspirin?

Phil questions if calcium interferes with absorption of other minerals such as magnesium.

What causes dry macular degeneration?  Can it be reversed?  Stop deteriorating capillaries.  Aspirin is generally protective. 

How to increase B vitamins?  Balanced diet.  Low-fat.

Can methylene blue be taken with sirolimus tablet?  MB is an electron donor and receptor.  Used for Alzheimer’s, depression.

What to do for Ankylosing Spondylitis?  

Why is ivermectin helpful?  Anti-inflammatory effect, parasite killer.

What are good brands of canned oysters?  Crown Prince in olive oil taste good, don’t know about toxins.  South American sourced preferable.

Oysters are rich in sea minerals.  Selenium, copper, etc.  Lobster also good.

Chris wants to know what to do about very dry skin and says PUFAS are all that seem to help.  Correct thyroid function to oil and moisturize skin.

Dr. Peat recommends TSH of 0.5 and below.  Says PUFA levels in blood can throw off T3 and T4.  Macadamia nuts and cashews are good because low in PUFAs.

Avoid cottonseed, canola, soy, corn oils.  A little cacao blocks the PUFA in canola.

How to shrink a large prostate?  Progesterone, aspirin, thyroid.

Don’t need to take the full dose of an antibiotic.

L. reuteri, bacillus subtilus cultures for yogurt.

Listener asks why he’s gained fat after using progesterone cream on neck and oral DHEA?  Progesterone creams aren’t absorbed on the skin.

Is iodine recommended for someone in a goiter zone?  A little bit of iodized salt is good.  Nodules and cancer of thyroid also affected by iodine.

Is a small amount of T4 at night recommended?  If having stressful nights.  The body doesn’t release endogenous thyroid all at once in the morning, better to space out during day.

Estrogen inhibits conversion of T4 to active T3.  Is why women have 10 times incidence of hypothyroidism.

If thyroid low, get thin, frail hairs.

Systemic enzymes get rid of fibrin and blood clots.  Does aspirin act the same way?  Antigenic traces of fungus in systemic enzymes.  Pancreatic enzymes carry risk of infections, but are the best choice.

What is a good cortisol level?

Good supplements for persistent cough and inflamed intestine from COVID?  Serotonin, easy to digest foods, keeping CO2 up. 

How low can saturated oxygen level go?  Would CO2 be helpful?  Baking soda regulates pH. 

What causes paronychia?  Vitamin A around nails.

Would eating farm raised chickens 4-5 times a week be harmful because of high Omega 6?  Yes.  US chicken and pork have more than 30% PUFAs. 

Recommendations for sagging and extremely dehydrated skin?  Thyroid regulates hydration and oil in skin.

Anxiety is a suppressor of the thyroid.  Great shock and accidents are often a trigger for turning the thyroid off.  Fear campaigns today are harming everyone’s bodies and minds.

Dr. Peat likes Dr. Bhakti’s thinking and his assertion that COVID and the vaccine are criminal and chemical warfare.

What causes lupus?  How to help broken capillaries?  Change diet, supplement thyroid and progesterone, avoid allergens.  From too much estrogen.

How much protein is Dr. Peat doing?  50 – 60 mg/daily.

Listener calls about an atrial fibrillation episode and her treatments.  Could the 4 cookies she ate just before the onset be the trigger?  Yes, intestinal disturbances can disturb heart rhythm.

How much orange juice does Dr. Peat drink every day?  A quart, for the anti-inflammatory effects.  Now trying a pint of concord grape juice and a pint of orange juice. 

What to do for bruxism?  Improve digestion.  Intestinal disturbances disturb serotonin.

Good alternatives to eating oysters and shellfish?  Get selenium.


'Dr. Ray Peat, Ph.D – Your Health Questions Answered – March 23, 2022' have 7 comments

  1. March 24, 2022 @ 10:33 am David Clark

    I was a bit surprised to hear Dr. Peat say that topical progesterone did not get absorbed, without taking thousands of milligrams. In the past, I have heard him promote topical use of nutrients and pre-hormones like DHEA, pregnenolone, etc. Some people like Georgi Dinkov says that topical showed better results systemically. In the next podcast, I would ask Dr. Peat if there are any benefits to topical application of nutrients and hormones, especially since he reputedly uses some himself.


    • March 30, 2022 @ 7:00 am Schultz

      You can listen to the 3 part Politics and Science episodes on progesterone to hear him talk about this more. Ray has commented that even Progest-e only absorbs around 20% when applied topically (although it obviously depends). Patrick asked specifically about a progesterone “cream” though, and they tend to have a bit of water in them. These products are basically useless topically as progesterone is very lipophillic and will crystallize out of solution when water is present (as far as I understand it).

      Other things (vitamins, various hormones) can absorb through the skin, but it depends on the solvent and the nutrient as to how well it absorbs, and other things like whether you recently bathed or not (since it alters the skin surface).


      • April 3, 2022 @ 9:52 am Helen

        Thank you for your detailed response, makes a lot of sense.
        Link to the 3 part Politics & Science please? I tried to google it, got all non-related links!


    • April 9, 2022 @ 9:29 am Anthony

      MY group uses a BIOMIMETIC hormone replacement protocol that replicates the youthful rhythms. All hormones are cream based and if the women is intact (has a uterus), they will bleed (a light 3 dayish bleed). The creams clearly build and shed the lining. Topical (if prepared properly) absolutely go systemic. If they did not, we would not be buidling the lining and then shedding the lining appropriately. I have not listend to the episode so CONTEXT would be important as usual.


    • May 12, 2022 @ 4:12 pm Kay

      David Clark- I had no idea on the progesterone application. May start applying to gums, as he indicates for Progest-E,


  2. March 24, 2022 @ 12:13 pm Kira Miftari

    It definitrly gets absorbed- this why and how bio-identical hormones work , and it is reflected by the subsequent change in hormone lab values


  3. March 24, 2022 @ 1:59 pm pb

    For some of us, life is one ongoing and grand experiment.
    Theorizing, testing, sharing, and expanding.
    RayPeat yourself.
    And become a legend…


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